pentobarbital will lessen the extent or result of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Powerful or reasonable CYP3A4 inducers might boost charge of diazepam elimination; for that reason, efficacy of diazepam can be diminished.pentobarbital will reduce the extent or influence of theophylline